Therapeutic treatment of dry skin

申请公布号：

US4105783(A)

申请号：

US19760720835

申请日期：

1976.09.07

申请公布日期：

1978.08.08

申请人：

YU, RUEY J.;VAN SCOTT, EUGENE J.

发明人：

YU, RUEY J.;VAN SCOTT, EUGENE J.

分类号：

A61K8/365;A61K9/00;A61K31/14;A61K31/16;A61K31/19;A61K47/10;A61Q19/00;(IPC1-7):A61K31/35

主分类号：

A61K8/365

摘要：

Preventive as well as therapeutic treatment to alleviate the symptoms of disorders characterized by cracking, flaking or scaling of the skin consisting of the topical application of a lotion, cream or ointment containing one or more of the alpha - or beta -hydroxy acids or alpha -keto acids and esters thereof, their amides and their ammonium salts is disclosed. The compounds include free acid, amide and/or ammonium salt forms of citric acid, glycolic acid, glucoronic acid, galacturonic acid, glucuronolactone, gluconolactone, alpha -hydroxybutyric acid, alpha -hydroxyisobutyric acid, lactic acid, malic acid, mandelic acid, mucic acid, pyruvic acid, methyl pyruvate, ethyl pyruvate, beta -phenyllactic acid, beta -phenylpyruvic acid, saccharic acid, tartaric acid, tartronic acid, and beta -hydroxybutyric acid. The therapeutic composition may include one or more of the compounds present in the total amount of from one to twenty percent. Topical application to affected areas has been found to achieve amelioration of the dry skin.