Heparin and heparinoid salts with organic bases - e.g. di:ethylamine, tri:ethanolamine, tri:ethylamine or buphenine
- 申请公布号：
- DE3020220(A1)
- 申请号：
- DE19803020220
- 申请日期：
- 1980.05.28
- 申请公布日期：
- 1981.12.03
- 申请人：
- ECKERT, THEODOR, PROF. DR., 4400 MUENSTER, DE
- 发明人：
- ECKERT, THEODOR, PROF. DR., 4400 MUENSTER, DE
- 分类号：
- C08B37/10;(IPC1-7):08B37/10;07C91/34;61K31/725
- 主分类号：
- C08B37/10
- 摘要：
- <p>Salts of heparin and heparinoids with organic bases (esp. diethylamine, triethanolamine, triethylamine, bamethan base, etilefrin base, buphenine base and other phenethylamine derivs.) are new. The new salts are prepd. by reaction of heparin or heparinoid with an equivalent or subequivalent amt. of an organic base. When the organic base is one which is volatile, equivalence can be established by removal of excess base under slight vacuum. The new salts show good absorption properties when applied topically (e.g. in the form of ointments, emulsions, solns. or gels) or rectally.</p>
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