MANUFACTURE OF POLY-BETA-ALANINE

申请公布号：

JPH0395222(A)

申请号：

JP19900154117

申请日期：

1990.06.14

申请公布日期：

1991.04.19

申请人：

L'OREAL SA

发明人：

KUROODO RAPOWARIERU;KUROODO MAIU;KURISUTORO PAPANTONIOO

分类号：

A61K9/14;A61K8/04;A61K8/35;A61K8/49;A61K8/67;A61K8/88;A61K9/16;A61K47/42;A61L26/00;A61Q7/00;A61Q13/00;A61Q17/04;A61Q19/00;C08F220/56;C08G69/00

主分类号：

A61K9/14

摘要：

Process for the preparation of crosslinked poly- beta -alanine in the form of microspheres with a narrow size distribution. <??>This process, which is carried out in a single stage, consists in polymerising acrylamide with a polyfunctional compound capable of being copolymerised with acrylamide, as a crosslinking agent, in an organic solvent or a mixture of such salts in the presence of an anionic polymerisation initiator and of a suspending agent. <??>Use of the microspheres obtained for impregnating a pharmaceutical or cosmetic active substance.