New oral formulation of two active ingredients II

申请公布号:
SE9600072(D0)
申请号:
SE19960000072
申请日期:
1996.01.08
申请公布日期:
1996.01.08
申请人:
ASTRA AB
发明人:
HELENE *DEPUI;AGNETA *HALLGREN
分类号:
C07D401/12;A61K9/26;A61K9/28;A61K9/48;A61K9/52;A61K31/44;A61K31/4427;A61K31/445;A61K45/06;A61P1/04;(IPC1-7):A61K/
主分类号:
C07D401/12
摘要:
PCT No. PCT/SE96/01736 Sec. 371 Date Feb. 13, 1997 Sec. 102(e) Date Feb. 13, 1997 PCT Filed Dec. 20, 1996 PCT Pub. No. WO97/25065 PCT Pub. Date Jul. 17, 1997An oral pharmaceutical dosage form comprising a proton pump inhibitor and one or more prokinetic agents in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer. The fixed formulation is in the form of multilayered tablets, capsules or multiple unit tableted dosage forms. The multiple unit dosage forms are most preferred. The new fixed formulation is especially useful in the treatment of disorders associated with gastro oesophageal reflux diseases.
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