METHOD FOR POLYURETHANE COATING ON SURFACE OF MEDICAL DEVICE
- 申请公布号：
- JPH11226114(A)
- 申请号：
- JP19980050201
- 申请日期：
- 1998.02.16
- 申请公布日期：
- 1999.08.24
- 申请人：
- NIPPON ZEON CO LTD
- 发明人：
- SAKAI KOICHI
- 分类号：
- A61L29/00;A61L31/00;A61L33/00;B32B27/34;B32B27/40;C09D175/04
- 主分类号：
- A61L29/00
- 摘要：
- PROBLEM TO BE SOLVED: To form a strong polyurethane coating layer having high peeling strength on the surface of an acid amide group content resin medical device by forming a polyurethane coating layer on the surface of the base material after N-acilating the acid amid group on at least surface of this group-containg resin base material. SOLUTION: A polyurethane coating layer is formed on the surface of a medical device composed of an acid amide group-containing resin base material such as a catheter, an introducer, a sheath, and a syringe so as to provide it with anti-thrombus performance. The polyurethane coating layer is formed before or after molding the resin base material into the form of the medical device and in this case, an acid amide group on at least surface of the resin base material is N-acilated so as to form a polyurethane coating layer on the surface of the base material. The N-acilation is implemented by dipping the resin base material in the solution of acilating agent such as acetylation agent, or spraying or applying the solution on the surface of the resin base material.
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