Solid phase synthesis of compounds by carbon-carbon bond forming mitsunobu reactions
- 申请公布号：
- AU5683799(A)
- 申请号：
- AU19990056837
- 申请日期：
- 1999.08.19
- 申请公布日期：
- 2000.03.14
- 申请人：
- THE PERKIN-ELMER CORPORATION
- 发明人：
- SURENDRAKUMAR CHATURVEDI
- 分类号：
- C07D243/08;C07B37/04;C07B61/00;C07C231/12;C07C233/65;C07C235/84;C07C253/30;C07C255/41;C07C255/42;C07C315/04;C07C317/44;C07C317/50;C07D231/20;C07D231/52;C07D239/46;C07D239/54;C07D239/60;C07D239/62;C07D239/66;C07F9/40;C40B40/04;C40B50/00
- 主分类号：
- C07D243/08
- 摘要：
- Processes are provided for the Mitsunobu alkylation reaction of carbon-carbon bond formation between a solid support reagent and a reagent in solution. The resulting novel products can be prepared as a combinatorial library by high-throughput, parallel synthesis under robotic automation. Cleaved or support-bound products are useful precursors to biologically active compounds.
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