BENZIMIDAZOLE DERIVATIVES

申请公布号：

CA2396908(A1)

申请号：

CA20012396908

申请日期：

2001.01.17

申请公布日期：

2001.07.26

申请人：

TEIJIN LIMITED

发明人：

MATSUMOTO, YOSHIYUKI;SAITOU, HIROSHI;TSUCHIYA, NAOKI;MIZUNO, TSUYOSHI

分类号：

A61K31/4184;A61P3/14;A61P9/00;A61P11/00;A61P29/00;A61P37/08;A61P43/00;C07D403/06;C07D409/06;(IPC1-7):C07D403/06;A61K31/418

主分类号：

A61K31/4184

摘要：

Benzimidazole derivatives of the general formula (1) or medically acceptable salts thereof, being useful as clinically applicable human chymase depressants, wherein R1 and R2 are each hydrogen, alkyl, alkoxy, or the like ; A is alkylene or alkenylene; E is -COOR3, -SO3R3, -CONHR3, -SO2NHR3, or the like; G is alkylene; M is a single bond or -S(O)m-; J is heteroaryl; and X i s - CH= or nitrogen.