NEUROTROPHIC FACTOR-LIKE AGENT

申请公布号：

JP2002255819(A)

申请号：

JP20010387935

申请日期：

2001.12.20

申请公布日期：

2002.09.11

申请人：

NIKKEN CHEM CO LTD

发明人：

YAMANA KENSHIRO;OSE TAKUTO

分类号：

C07D215/42;A61K31/473;A61P25/16;A61P25/28;A61P43/00;(IPC1-7):A61K31/473

主分类号：

C07D215/42

摘要：

PROBLEM TO BE SOLVED: To provide a neurotrophic factor-like agent scarcely exhibiting side effects. SOLUTION: This neurotrophic factor-like agent contains ipidacrine (9- amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinoline), its hydrate, or its pharmacologically acceptable salt, preferably, hydrated ipidacrine hydrochloride, as an active ingredient. The hydrated ipidacrine hydrochloride or the like usefully acts as a prophylactic or remedy for neuropathic diseases (senile dementia, Alzheimer's dementia, Down's syndrome, Parkinson's disease, Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, diabetic neuropathy, etc.), and neuropathic disorders caused by cerebrovascular accident, head injury, spinal cord lesion, etc.