REPAIRING AGENT FOR FIBROSING LESION TISSUE

申请公布号：

JP2003335672(A)

申请号：

JP20020144720

申请日期：

2002.05.20

申请公布日期：

2003.11.25

申请人：

AJINOMOTO CO INC

发明人：

CHIBA AKIRA;MATSUMOTO HIDEKI;TANAKA YASUHIRO;IJICHI CHIORI;OMUTA NAOKO;TAKATSUKI FUMIHIKO

分类号：

C07D231/26;A61K31/4152;A61K31/4155;A61K31/4196;A61K31/4439;A61P1/16;A61P9/00;A61P9/10;A61P11/00;A61P13/08;A61P13/12;A61P17/02;A61P19/02;A61P37/00;A61P41/00;A61P43/00;C07D231/28;C07D231/52;C07D401/04;C07D403/04;(IPC1-7):A61K31/415;A61K31/415;A61K31/419;A61K31/443

主分类号：

C07D231/26

摘要：

PROBLEM TO BE SOLVED: To obtain an excellent repairing agent for fibrosing lesion tissue or an inhibitor against the formation of fibrosing lesion for a patient suffering from a disease caused by morbid accumulation of collagen fiber, or the like, e.g. hepatic fibrosis such as cirrhosis, pulmonary fibrosis, renal fibrosis, arteriosclerosis, systemic sclerosis, prostatic hypertrophy, keloidosis, cardiomyopathy, collagen disease and cicatrices. SOLUTION: The repairing agent for the fibrosing lesion tissue or the inhibitor against the formation of the fibrosing lesion contains a pyrazolone derivative represented by the formula, an analogue thereof or a pharmaceutically acceptable salt thereof. COPYRIGHT: (C)2004,JPO