INHIBITION OF TUMOR CELL PROLIFERATION BY FOXM1B INHIBITORS
- 申请公布号：
- WO2004100977(A1)
- 申请号：
- WO2004US09454
- 申请日期：
- 2004.03.25
- 申请公布日期：
- 2004.11.25
- 申请人：
- THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS;COSTA, ROBERT, H.;RAYCHAUDHURI, PRADIP;WANG, XINHE;KALINICHENKO, VLADIMIR;MAJOR, MICHAEL;WANG, I-CHING
- 发明人：
- COSTA, ROBERT, H.;RAYCHAUDHURI, PRADIP;WANG, XINHE;KALINICHENKO, VLADIMIR;MAJOR, MICHAEL;WANG, I-CHING
- 分类号：
- A61K31/00;A61K31/277;A61K31/55;A61K38/17;A61K48/00;A61P35/00;C12N15/113;G01N33/574;(IPC1-7):A61K38/17;C12N15/11;G01N33/50
- 主分类号：
- A61K31/00
- 摘要：
- <p>The invention provides methods for inhibiting tumor cell proliferation by inhibiting FoxM1B activity, expression, or nuclear localization in a tumor cell. The invention also provides methods for preventing tumor progression in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization. Furthermore, the invention provides methods for inhibiting tumor cell growth in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization in tumor cells in the animal.</p>
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