Chemoablation of tissue using biodegradable, solid salt dosage forms
- 申请公布号：
- US2005064046(A1)
- 申请号：
- US20040940589
- 申请日期：
- 2004.09.14
- 申请公布日期：
- 2005.03.24
- 申请人：
- DITROLIO JOSEPH V.
- 发明人：
- DITROLIO JOSEPH V.
- 分类号：
- A61K33/14;A61M5/315;A61M31/00;A61M37/00;(IPC1-7):A61K33/14
- 主分类号：
- A61K33/14
- 摘要：
- Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated.
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