Solid dispersions comprising two different polymer matrixes
- 申请公布号：
- US7407670(B2)
- 申请号：
- US20040518987
- 申请日期：
- 2004.12.21
- 申请公布日期：
- 2008.08.05
- 申请人：
- JANSSEN PHARMACEUTICA, N.V.
- 发明人：
- SIX KAREL;VERRECK GEERT;PEETERS JOZEF;BREWSTER MARCUS ELI;VAN DEN MOOTER GUY
- 分类号：
- A61K9/14;A61K9/50;A61K9/00;A61K9/16;A61K31/496;A61K47/30;A61K47/32;A61K47/38;A61P31/10
- 主分类号：
- A61K9/14
- 摘要：
- Present invention provides solid dispersions comprising a poorly soluble bioactive compound dispersed in a polymer matrix characterized in that the polymer matrix comprises more than one polymer. Said solid dispersions effectively stabilize the dispersed compound while stimulating the solubilisation of the compound in an aquaeous environment.
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