POLYPEPTIDES AND BIOSYNTHETIC PATHWAYS FOR THE PRODUCTION OF STEREOISOMERS OF MONATIN AND THEIR PRECURSORS
- 申请公布号：
- WO2007133184(A3)
- 申请号：
- WO2006US15930
- 申请日期：
- 2006.04.26
- 申请公布日期：
- 2008.08.28
- 申请人：
- CARGILL, INCORPORATED;BRAZEAU, BRIAN J.;BURKE, ELLEN;DE SOUZA, MERVYN;GORT, STEVEN J.;HICKS, PAULA M.;KOLLMAN, SHERRY R.;LUGINBUHL, PETER;MCFARLAN, SARA, C.;RICHARDSON, TOBY;SANCHEZ-RIERA, FERNANDO A.;SOLHEID, CHRISTOPHER;WEINER, DAVID;ZHAO, LISHAN
- 发明人：
- BRAZEAU, BRIAN J.;BURKE, ELLEN;DE SOUZA, MERVYN;GORT, STEVEN J.;HICKS, PAULA M.;KOLLMAN, SHERRY R.;LUGINBUHL, PETER;MCFARLAN, SARA, C.;RICHARDSON, TOBY;SANCHEZ-RIERA, FERNANDO A.;SOLHEID, CHRISTOPHER;WEINER, DAVID;ZHAO, LISHAN
- 分类号：
- C12N9/10;C12N1/21;C12P13/22
- 主分类号：
- C12N9/10
- 摘要：
- Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
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