Bone substitute, and method for the preparation thereof
- 申请公布号：
- AU2009267812(B2)
- 申请号：
- AU20090267812
- 申请日期：
- 2009.06.26
- 申请公布日期：
- 2014.12.18
- 申请人：
- UNIVERSITE PIERRE ET MARIE CURIE PARIS VI;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;ECOLE PRATIQUE DES HAUTES ETUDES
- 发明人：
- NASSIF, NADINE;MOSSER, GERVAISE;GOBEAUX, FREDERIC;GIRAUD GUILLE, MARIE MADELEINE
- 分类号：
- A61L27/12
- 主分类号：
- A61L27/12
- 摘要：
- The invention relates to a material that can be used as a bone substitute and to a method for the preparation thereof. The material comprises an organic phase (I) comprising striated collagen fibrils constituted of collagen I triple helices, said fibrils being organized over a large distance according to a 3D geometry associating aligned domains and cholesteric domains, and also isotropic domains where they are not organized; and a mineral phase (II) comprising apatite crystals having a hexagonal crystalline structure, space group 6/m, comprising at least calcium ions and phosphate ions; the axis
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