Virus causing respiratory tract illness in susceptible mammals

申请公布号:
US8927206(B2)
申请号:
US200210466811
申请日期:
2002.01.18
申请公布日期:
2015.01.06
申请人:
ViroNovative B.V.
发明人:
De Jong Jan Cornelius;Fouchier Ronaldus Adrianus Maria;Van Den Hoogen Bernadetta Gerarda;Osterhaus Albertus Dominicus Marcellinus Erasmus;Groen Jan
分类号:
C12Q1/70;C12N15/86;C07K14/005;C12N7/00;A61K39/00
主分类号:
C12Q1/70
代理机构:
TraskBritt, P.C.
代理人:
TraskBritt, P.C.
地址:
Rotterdam NL
摘要:
The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single stranded RNA virus (MPV) within the sub-family Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
主权项:
1. A method for identifying a viral isolate from a mammalian subject as comprising a human metapneumovirus, the method comprising: reacting the viral isolate or a component thereof with a DNA molecule of at least 10 nucleotides in length that is at least 90% homologous to a stretch of the DNA sequence of SEQ ID NO: 36, or the complement thereof; wherein reaction of the DNA molecule with the viral isolate or component thereof indicates the presence of human metapneumovirus in the viral isolate from the mammalian subject.
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