METHOD AND MEANS FOR CARTILAGE REPAIR

申请公布号：

CA2178243(A1)

申请号：

CA19962178243

申请日期：

1996.06.05

申请公布日期：

1996.12.08

申请人：

HALPERN, ALAN A.

发明人：

HALPERN, ALAN A.

分类号：

A61F2/00;A61F2/02;A61F2/28;A61F2/30;A61K9/50;A61L27/18;A61L27/22;A61L27/38;A61L27/50;A61L27/56;A61L27/58;A61N2/10;(IPC1-7):A61K35/32;A61L27/00;A61K35/28

主分类号：

A61F2/00

摘要：

A method for repairing a defect in cartilage, comprising the provision of apertures in the cartilage by drilling holes at the base of the cartilage defect, which holes may enter the mesenchymal depot, introducing a porous scaffold material containing a plurality of magnetic particles into the apertures, and subsequently and sequentially injecting magnetically-tagged cartilage growth promoting materials such as various growth factors or chondrocytes into the area of the defect. The magnetically tagged growth promoting material is then drawn into the apertures by magnetic attraction of the magnetic particles contained in the porous scaffold material, either by virtue of the particles being permanently magnetic, or by the imposition of an external magnetic field. The present application claims the biodegradable porous scaffold material containing the plurality of magnetic particles.